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1

Pleiotropic neuroprotective and metabolic effects of Actovegin's mode of action

Fausto Machicao, Dafin Fior Muresanu, Harald Hundsberger, Maren Pflüger, Alla Guekht

Journal:

Journal of the Neurological Sciences

Year:

2012

Language:

english

File:

PDF, 377 KB

english, 2012

2

Effect of genetic variation in Kv1.3 on olfactory function

Martina Guthoff, Otto Tschritter, Daniela Berg, Inga Liepelt, Claudia Schulte, Fausto Machicao, Hans-Ulrich Haering, Andreas Fritsche

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2009

Language:

english

File:

PDF, 103 KB

english, 2009

3

Common polymorphisms within theNR4A3locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced β-cell function in non-diabetic subjects

Peter Weyrich, Harald Staiger, Alena Stančáková, Silke A Schäfer, Kerstin Kirchhoff, Susanne Ullrich, Felicia Ranta, Baptist Gallwitz, Norbert Stefan, Fausto Machicao, Johanna Kuusisto, Markku Laakso,

Journal:

BMC Medical Genetics

Year:

2009

Language:

english

File:

PDF, 1017 KB

english, 2009

4

No association between variation in theNR4A1gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes

Karsten Müssig, Fausto Machicao, Jürgen Machann, Fritz Schick, Claus D Claussen, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger

Journal:

BMC Medical Genetics

Year:

2010

Language:

english

File:

PDF, 326 KB

english, 2010

5

Association of obesity risk SNPs inPCSK1with insulin sensitivity and proinsulin conversion

Martin Heni, Axel Haupt, Silke A Schäfer, Caroline Ketterer, Claus Thamer, Fausto Machicao, Norbert Stefan, Harald Staiger, Hans-Ulrich Häring, Andreas Fritsche

Journal:

BMC Medical Genetics

Year:

2010

Language:

english

File:

PDF, 581 KB

english, 2010

6

SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention – the TULIP Study

Peter Weyrich, Fausto Machicao, Julia Reinhardt, Jürgen Machann, Fritz Schick, Otto Tschritter, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring

Journal:

BMC Medical Genetics

Year:

2008

Language:

english

File:

PDF, 324 KB

english, 2008

7

Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene–gene interactions

Konstantinos Kantartzis, Andreas Fritsche, Fausto Machicao, Michael Stumvoll, Jürgen Machann, Fritz Schick, Hans-Ulrich Häring, Norbert Stefan

Journal:

Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 183 KB

english, 2007

8

Genetic variation within theNR1H2gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes

Caroline Ketterer, Karsten Müssig, Fausto Machicao, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 155 KB

english, 2011

9

Interaction effect between common polymorphisms in PPARγ2(Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity

Michael Stumvoll, Norbert Stefan, Andreas Fritsche, Alexander Madaus, Otto Tschritter, Matthias Koch, Fausto Machicao, Hans Häring

Journal:

Journal of Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

10

A method for quantitative determinations of nonhistone proteins in chromatin

Johann Sonnenbichler, Isolde Zetl, Fausto Machicao

Journal:

Analytical Biochemistry

Year:

1975

Language:

english

File:

PDF, 284 KB

english, 1975

11

In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor δ reflects donors’ insulin sensitivity in vivo

Anna-Maria Ordelheide, Martin Heni, Claus Thamer, Fausto Machicao, Andreas Fritsche, Norbert Stefan, Hans-Ulrich Häring, Harald Staiger

Journal:

European Journal of Clinical Investigation

Year:

2011

Language:

english

File:

PDF, 183 KB

english, 2011

12

GENETIC STUDY: Significant impact of MTHFR C677T polymorphism on plasma homovanillic acid (HVA) levels among alcohol-dependent patients

Ulrich C. Lutz, Anil Batra, Gerlinde Wiatr, Fausto Machicao, Werner Kolb, Sandra Maurer, Gerhard Buchkremer, Michael D. Köhnke

Journal:

Addiction Biology

Year:

2007

Language:

english

File:

PDF, 93 KB

english, 2007

13

Methylenetetrahydrofolate Reductase C677T-Polymorphism and Its Association With Alcohol Withdrawal Seizure

Ulrich C. Lutz, Anil Batra, Werner Kolb, Fausto Machicao, Sandra Maurer, Michael D. Köhnke

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

14

C825T Polymorphism of the G Protein β3 Subunit Is Associated with Obesity but Not with Insulin Sensitivity

Norbert Stefan, Michael Stumvoll, Fausto Machicao, Matthias Koch, Hans U. Häring, Andreas Fritsche

Journal:

Year:

2004

Language:

english

File:

PDF, 80 KB

english, 2004

15

Impact of Variation in the FTO Gene on Whole Body Fat Distribution, Ectopic Fat, and Weight Loss

Axel Haupt, Claus Thamer, Jürgen Machann, Kerstin Kirchhoff, Norbert Stefan, Otto Tschritter, Fausto Machicao, Fritz Schick, Hans-Ulrich Häring, Andreas Fritsche

Journal:

Year:

2008

Language:

english

File:

PDF, 150 KB

english, 2008

16

Adiponectin Oligomers and Ectopic Fat in Liver and Skeletal Muscle in Humans

Konstantinos Kantartzis, Harald Staiger, Jürgen Machann, Fritz Schick, Claus D. Claussen, Fausto Machicao, Andreas Fritsche, Hans-Ulrich Häring, Norbert Stefan

Journal:

Year:

2009

Language:

english

File:

PDF, 127 KB

english, 2009

17

Impact of Variation Near MC4R on Whole-body Fat Distribution, Liver Fat, and Weight Loss

Axel Haupt, Claus Thamer, Martin Heni, Otto Tschritter, Jürgen Machann, Fritz Schick, Fausto Machicao, Hans-Ulrich Häring, Harald Staiger, Andreas Fritsche

Journal:

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

18

Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study

Axel Haupt, Claus Thamer, Martin Heni, Fausto Machicao, Jürgen Machann, Fritz Schick, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger

Journal:

Year:

2010

Language:

english

File:

PDF, 124 KB

english, 2010

19

Variants in the CD36 Gene Locus Determine Whole-Body Adiposity, but Have No Independent Effect on Insulin Sensitivity

Martin Heni, Karsten Müssig, Fausto Machicao, Jürgen Machann, Fritz Schick, Claus D. Claussen, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger

Journal:

Year:

2011

Language:

english

File:

PDF, 119 KB

english, 2011

20

RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study

Karsten Müssig, Harald Staiger, Fausto Machicao, Claus Thamer, Jürgen Machann, Fritz Schick, Claus D. Claussen, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring

Journal:

Year:

2009

Language:

english

File:

PDF, 185 KB

english, 2009

21

Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

Karsten Müssig, Harald Staiger, Fausto Machicao, Jürgen Machann, Fritz Schick, Silke A. Schäfer, Claus D. Claussen, Jens J. Holst, Baptist Gallwitz, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Härin

Journal:

Year:

2009

Language:

english

File:

PDF, 95 KB

english, 2009

22

Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes

Caroline Ketterer, Karsten Müssig, Martin Heni, Katarzyna Dudziak, Elko Randrianarisoa, Robert Wagner, Fausto Machicao, Norbert Stefan, Jens J. Holst, Andreas Fritsche, Hans-Ulrich Häring, Harald Stai

Journal:

Year:

2011

Language:

english

File:

PDF, 250 KB

english, 2011

23

Effects of Troglitazone on Cellular Differentiation, Insulin Signaling, and Glucose Metabolism in Cultured Human Skeletal Muscle Cells

Christiana Kausch, Jan Krützfeldt, Anja Witke, Alke Rettig, Oliver Bachmann, Kristian Rett, Stephan Matthaei, Fausto Machicao, Hans-Ulrich Häring, Michael Stumvoll

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 416 KB

english, 2001

24

Stimulation of phospholipase C activity by insulin is mediated by both isotypes of the human insulin receptor

Monika Kellerer, Fausto Machicao, Eva Seffer, Joanne Mushack, Axel Ullrich, Hans Ulrich Häring

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 436 KB

english, 1991

25

Inflammatory response of human coronary artery endothelial cells to saturated long-chain fatty acids

Alexander Krogmann, Katrin Staiger, Carina Haas, Nadja Gommer, Andreas Peter, Martin Heni, Fausto Machicao, Hans-Ulrich Häring, Harald Staiger

Journal:

Microvascular Research

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

26

Effect of insulin detemir, compared to human insulin, on 3T3-L1 adipogenesis

Anja Böhm, Harald Staiger, Anita M. Hennige, Carina Haas, Fausto Machicao, Hans-Ulrich Häring

Journal:

Regulatory Peptides

Year:

2008

Language:

english

File:

PDF, 899 KB

english, 2008

27

Increased insulin clearance in peroxisome proliferator-activated receptor γ2 Pro12Ala

Otto Tschritter, Andreas Fritsche, Norbert Stefan, Michael Haap, Claus Thamer, Oliver Bachmann, Dominik Dahl, Elke Maerker, Anna Teigeler, Fausto Machicao, Hans Häring, Michael Stumvoll

Journal:

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

28

No influence of the PPARγ2 Pro12Ala genotype on serum adiponectin concentrations in healthy Europeans

Claus Thamer, Fausto Machicao, Andreas Fritsche, Michael Stumvoll, Hans Häring

Journal:

Year:

2003

Language:

english

File:

PDF, 31 KB

english, 2003

29

Missense mutations in the insulin promoter factor-1 gene in a healthy German population are not associated with decreased insulin secretion

Fausto E Machicao, Andreas Fritsche, Michael Stumvoll, Melanie Weisser, Alke Rettig, Erwin Schleicher, Hans Ulrich Haering

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 146 KB

english, 2000

30

New type 2 diabetes risk genes provide new insights in insulin secretion mechanisms

Silke A. Schäfer, Fausto Machicao, Andreas Fritsche, Hans-Ulrich Häring, Konstantinos Kantartzis

Journal:

Diabetes Research and Clinical Practice

Year:

2011

Language:

english

File:

PDF, 531 KB

english, 2011

31

Association of peroxisome proliferator–activated receptor gamma 2 Pro-12-Ala polymorphism with endometriosis

Songuel Dogan, Fausto Machicao, Diethelm Wallwiener, Hans-Ulrich Haering, Klaus Diedrich, Daniela Hornung

Journal:

Fertility and Sterility

Year:

2004

Language:

english

File:

PDF, 52 KB

english, 2004

32

Genetic variation within the ANGPTL4 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

Harald Staiger, Fausto Machicao, Roman Werner, Alke Guirguis, Melanie Weisser, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring

Journal:

Year:

2008

Language:

english

File:

PDF, 282 KB

english, 2008

33

Association of the ACE gene I/D polymorphism with insulin sensitivity depends on the presence of additional macroangiopathic risk factors

Claus Thamer, Matthias Koch, Michael Haap, Fausto Machicao, Hans-Ulrich Häring, Michael Stumvoll

Journal:

Atherosclerosis

Year:

2002

Language:

english

File:

PDF, 58 KB

english, 2002

34

Fetuin-A Induces Cytokine Expression and Suppresses Adiponectin Production

Hennige, Anita M., Staiger, Harald, Wicke, Corinna, Machicao, Fausto, Fritsche, Andreas, Häring, Hans-Ulrich, Stefan, Norbert, Bartolomucci, Alessandro

Journal:

Year:

2008

Language:

english

File:

PDF, 312 KB

english, 2008

35

Genetic variants in MTNR1B affecting insulin secretion

Müssig, Karsten, Staiger, Harald, Machicao, Fausto, Häring, Hans-Ulrich, Fritsche, Andreas

Journal:

Annals of Medicine

Year:

2010

Language:

english

File:

PDF, 182 KB

english, 2010

36

Polymorphism rs3123554 in CNR2 reveals gender-specific effects on body weight and affects loss of body weight and cerebral insulin action

Ketterer, Caroline, Heni, Martin, Stingl, Krunoslav, Tschritter, Otto, Linder, Katarzyna, Wagner, Robert, Machicao, Fausto, Häring, Hans-Ulrich, Preissl, Hubert, Staiger, Harald, Fritsche, Andreas

Journal:

Year:

2014

Language:

english

File:

PDF, 714 KB

english, 2014

37

Pathomechanisms of Type 2 Diabetes Genes

Staiger, Harald, Machicao, Fausto, Fritsche, Andreas, Häring, Hans-Ulrich

Journal:

Endocrine Reviews

Year:

2009

Language:

english

File:

PDF, 351 KB

english, 2009

38

The genetic influence on body fat distribution

Wagner, Robert, Machicao, Fausto, Fritsche, Andreas, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald

Journal:

Drug Discovery Today: Disease Mechanisms

Year:

2013

Language:

english

File:

PDF, 826 KB

english, 2013

39

Nor-1, a novel incretin-responsive regulator of insulin genes and insulin secretion

Ordelheide, Anna-Maria, Gerst, Felicia, Rothfuss, Oliver, Heni, Martin, Haas, Carina, Thielker, Inga, Herzberg-Schäfer, Silke, Böhm, Anja, Machicao, Fausto, Ullrich, Susanne, Stefan, Norbert, Fritsche

Journal:

Molecular Metabolism

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

40

The C514T polymorphism in the human hepatic Lpase gene promoter is associated with altered lipid metabolism during euglycemic hyperinsulinemia in obese men with a history of type 2 diabetes

Machicao, Fausto E, Fritsche, Andreas, Weisser, Melanie, Rettig, Alke, Haering, Hans Ulrich, Stumvoll, Michael

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

41

Variation in the obesity risk gene FTO determines the postprandial cerebral processing of food stimuli in the prefrontal cortex

Heni, Martin, Kullmann, Stephanie, Veit, Ralf, Ketterer, Caroline, Frank, Sabine, Machicao, Fausto, Staiger, Harald, Häring, Hans-Ulrich, Preissl, Hubert, Fritsche, Andreas

Journal:

Molecular Metabolism

Year:

2014

Language:

english

File:

PDF, 382 KB

english, 2014

42

Clinical and non-targeted metabolomic profiling of homozygous carriers of Transcription Factor 7-like 2 variant rs7903146

Wagner, Robert, Li, Jia, Kenar, Erhan, Kohlbacher, Oliver, Machicao, Fausto, Häring, Hans-Ulrich, Fritsche, Andreas, Xu, Guowang, Lehmann, Rainer

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 366 KB

english, 2014

43

Association of Common Genetic Variation in the FOXO1 Gene with β-Cell Dysfunction, Impaired Glucose Tolerance, and Type 2 Diabetes

Müssig, Karsten, Staiger, Harald, Machicao, Fausto, Stančáková, Alena, Kuusisto, Johanna, Laakso, Markku, Thamer, Claus, Machann, Jürgen, Schick, Fritz, Claussen, Claus D., Stefan, Norbert, Fritsche,

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2009

Language:

english

File:

PDF, 168 KB

english, 2009

44

Treatment with Actovegin improves spatial learning and memory in rats following transient forebrain ischaemia

Meilin, Sigal, Machicao, Fausto, Elmlinger, Martin

Journal:

Journal of Cellular and Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 602 KB

english, 2014

45

Differential effect of glucose ingestion on the neural processing of food stimuli in lean and overweight adults

Heni, Martin, Kullmann, Stephanie, Ketterer, Caroline, Guthoff, Martina, Bayer, Margarete, Staiger, Harald, Machicao, Fausto, Häring, Hans-Ulrich, Preissl, Hubert, Veit, Ralf, Fritsche, Andreas

Journal:

Human Brain Mapping

Year:

2014

Language:

english

File:

PDF, 424 KB

english, 2014

46

Mechanism of the Stimulation of RNA Synthesis in Rat Liver Nuclei by Silybin

MACHICAO, Fausto, SONNENBICHLER, Johann

Journal:

Hoppe-Seyler's Zeitschrift für physiologische Chemie

Year:

1977

File:

PDF, 950 KB

1977

47

Subunit Structure of Dihydrolipoamide Acetyltransferase Component of Pyruvate Dehydrogenase Complex from Bovine Kidney

MACHICAO, Fausto, WIELAND, Otto H.

Journal:

Hoppe-Seyler's Zeitschrift für physiologische Chemie

Year:

1980

Language:

english

File:

PDF, 1.55 MB

english, 1980

48

Variations in PPARD Determine the Change in Body Composition during Lifestyle Intervention: A Whole-Body Magnetic Resonance Study

Thamer, Claus, Machann, Jürgen, Stefan, Norbert, Schäfer, Silke A., Machicao, Fausto, Staiger, Harald, Laakso, Markku, Böttcher, Michael, Claussen, Claus, Schick, Fritz, Fritsche, Andreas, Haring, Han

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 63 KB

english, 2008

49

The Myocyte Expression of Adiponectin Receptors and PPARδ Is Highly Coordinated and Reflects Lipid Metabolism of the Human Donors

Ordelheide, Anna-Maria, Heni, Martin, Gommer, Nadja, Gasse, Lisa, Haas, Carina, Guirguis, Alke, Machicao, Fausto, Häring, Hans-Ulrich, Staiger, Harald

Journal:

Experimental Diabetes Research

Year:

2011

Language:

english

File:

PDF, 662 KB

english, 2011

50

Lower Plasma Creatinine and Urine Albumin in Individuals at Increased Risk of Type 2 Diabetes with Factor V Leiden Mutation

Peter, Andreas, Fritsche, Andreas, Machicao, Fausto, Nawroth, Peter P., Häring, Hans-Ulrich, Isermann, Berend

Journal:

ISRN Endocrinology

Year:

2014

Language:

english

File:

PDF, 104 KB

english, 2014

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